抗 肌球蛋白轻链激酶抗体,小鼠单克隆,25UL,SAB4200808-25UL,Sigma

销售价: ¥ 1801.60 / 件
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订货号 0BQ0542
品牌型号 Sigma SAB4200808-25UL
货期 询货期
最小订货量 1件
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  • 商品介绍
  • 规格参数
  • 包装参数
产品介绍 Product Description

General description

Myosin Light Chain Kinase (MLCK) also known as MYLK is a Ca2+/calmodulin dependent myosin light chain phosphorylating agent. This enzyme plays a major role in the phosphorylation of the regulatory light chains of myosin which are essential for the shortening and tension development of smooth muscle cells resulting in smooth muscle contraction. Myosin light chain kinase are widely expressed in many different tissues and cells of eukaryote species. There are two genes mylk1 and mylk2 encoding the MLCK protein, mylk2 is exclusively expressed in skeletal muscle cells.


Immunogen

Purified chicken gizzard myosin light chain kinase.


Application

Monoclonal Anti-Myosin Light Chain Kinase recognizes the myosin light chain kinase of smooth muscle and from non-muscle cells such as cultured fibroblasts. Reactivity has been observed with myosin light chain kinase from chicken, turkey, bovine, human, mouseand pig origin. The antibody is recommended to use in various immunological techniques, including Immunoblotting (~160kDa), Immunohistochemistry and immunofluorescence.


Physical form

Supplied as a solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide as a preservative.


Other Notes

This product is for R&D use only, not for drug, household, or other uses.


技术参数 Specifications
biological sourcemouse
conjugateunconjugated
antibody formpurified from hybridoma cell culture
antibody product typeprimary antibodies
cloneK36, monoclonal
formbuffered aqueous solution
mol wt ~160 kDa
species reactivitybovine, human, mouse, chicken, pig, turkey
packagingantibody small pack of 25 μL
concentration~1 mg/mL
technique(s)immunoblotting: 0.25-0.5 μg/mL using chicken gizzard extract
isotypeIgG2b
UniProt accession no.Q15746
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
长度(mm)
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