Monoclonal Anti-TCR Vdelta2 purified produced in mouse,,SAB4702013-100UG,Sigma

销售价: ¥ 1365.28 / 件
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订货号 0BQ0543
品牌型号 Sigma SAB4702013-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

TCR Vdelta2 is a variant of TCR delta chain, that is present on a major subset of human gamma/delta T cells. TCR Vgamma9/Vdelta2 (or Vgamma2/Vdelta2) T cells are able to recognize and kill various tumor cells, as this receptor heterodimer binds to certain phosphoantigens, expressed by tumors. They can recognize these antigens in an MHC-unrestricted manner. Similarly to NK cells, Vdelta2 T cells express MHC I receptors and killer Ig-like receptors, that are involved in tumor recognition and cytolysis. The potently cytotoxic subset of them is identified by cell surface expression of polysialyated CD56.


Immunogen

human recombinant TCR Vdelta2


Biochem/physiol Actions

The mouse monoclonal antibody B6 recognizes an extracellular epitope of human TCR Vdelta2, which is expressed on the majority of gamma/delta T cells.


Physical form

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide


Preparation Note

Purified by protein-A affinity chromatography.
Store at 2-8°C. Do not freeze.


Other Notes

The antibody solution should be gently mixed before use.


技术参数 Specifications
conjugateunconjugated
Quality Segment100
antibody product typeprimary antibodies
cloneB6, monoclonal
formbuffered aqueous solution
species reactivityhuman
concentration1 mg/ml
technique(s)flow cytometry: suitable
isotypeIgG1κ
storage temp.2-8°C
target post-translational modificationunmodified
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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