Anti-TLR5 Antibody, clone 6P1Q10, Rabbit Monoclonal,100UL,SAB5702634-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BQ0577
品牌型号 Sigma SAB5702634-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009]


Immunogen

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Recombinant fusion protein containing a sequence corresponding to amino acids 258-404 of human TLR5 (O60602).


Application

WB


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
materialcolorless
clone6P1Q10, monoclonal
formliquid
mol wt 105 kDa
species reactivitymouse
concentration1.2mg/mL
technique(s)western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceLILAHHIMGAGFGFHNIKDPDQNTFAGLARSSVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLSYNLLGELYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTTIHFIPS
UniProt accession no.O60602
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... TLR5(7100)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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