Anti-RPA70 antibody produced in rabbit,100UL,SAB5701703-100UL,Sigma

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订货号 0BQ0688
品牌型号 Sigma SAB5701703-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a protein which is located in the retinal pigment epithelium and is involved in the production of 11-cis retinal and in visual pigment regeneration. There are two forms of this protein, a soluble form called sRPE65, and a palmitoylated, membrane-bound form known as mRPE65. mRPE65 serves as the palmitoyl donor for lecithin retinol acyl transferase (LRAT), the enzyme that catalyzes the vitamin A to all trans retinol step of the chromophore regeneration process. Both mRPE65 and sRPE65 also serve as regulatory proteins, with the ratio and concentrations of these molecules playing a role in the inhibition of 11-cis retinal synthesis. Mutations in this gene have been associated with Leber congenital amaurosis type 2 (LCA2) and retinitis pigmentosa. [provided by RefSeq, Jul 2008]


Immunogen

A synthesized peptide derived from human RPA70


Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
antibody product typeprimary antibodies
clonemonoclonal
formliquid
species reactivityhuman, mouse
concentration1.65 mg/mL
technique(s)immunohistochemistry: 1:50-1:200,western blot: 1:500-1:2000
UniProt accession no.Q16518
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... RPE65(6121)
长度(mm)
宽度(mm)
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重量(kg)
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