- 商品介绍
- 规格参数
- 包装参数
General description
CD27 Ligand, a type II transmembrane protein, is expressed on activated T and B lymphocytes as well as NK cells. CD27L and its receptor (CD27) regulate the immune response by promoting T-cell expansion and differentiation, as well as NK enhancement. CD27 signaling can act as a co-stimulatory effector to sustain the survival of CD8+ T cells, primarily by inducing increased expression of the IL-2 gene.
Biochem/physiol Actions
CD27 Ligand, a type II transmembrane protein, is a member of the TNF superfamily. Full length human CD27L is a 193 amino acid protein, consisting of a 17 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 155 amino acid extracellular domain. Human soluble CD27L corresponds to the 155 amino acid extracellular domain of the full length CD27L protein. Recombinant human sCD27L contains the extracellular domain plus an N-terminal His-Tag.
Physical form
Lyophilized from 20 mM Sodium Citrate, pH 3.0.
Preparation Note
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
| biological source | human |
| recombinant | expressed in CHO cells |
| assay | ≥95% (HPLC),≥95% (SDS-PAGE) |
| form | lyophilized |
| potency | 10.0-25.0 ng/mL |
| mol wt | 25.0-35.0 kDa |
| packaging | pkg of 50 μg |
| impurities | <0.1 EU/μg endotoxin, tested |
| color | white |
| UniProt accession no. | P32970 |
| shipped in | wet ice |
| storage temp. | −20°C |
| Gene Information | human ... CD70(970) |
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¥ 2707.32
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¥ 1683.78
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NNALGENE 180透明塑料管，透明，柔软，多用，经济，内径 x 外径x壁厚，1/4 x 1/2 x 1/8，英寸，每箱数量50，50/箱，8000-0080，Thermofisher，赛默飞世尔询价
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