PDGFR-α, active, GST tagged from mouse,10UG,SRP5254-10UG,Sigma

销售价: ¥ 3866.08 / 件
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订货号 0BQ1752
品牌型号 Sigma SRP5254-10UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

PDGFR alpha (platelet-derived growth factor receptor A) is a member of the PDGFR family of membrane receptors with intrinsic tyrosine kinase activity. Aberrant expression of PDGFR alpha has been linked to developmental abnormalities in vertebrate models and has been implicated in multiple disease states in humans. There is widespread expression of PDGFR alpha in renal cell types involved in fibrotic and sclerosing processes. PDGF and its receptor PDGFR alpha are inducers of fibrosis in the repair phase of inflammatory bowel disease and they may also be involved in the active inflammatory phase.


Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.


Preparation Note

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.


Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany


技术参数 Specifications
recombinantexpressed in baculovirus infected Sf9 cells
product linePRECISIO®
assay≥70% (SDS-PAGE)
formbuffered aqueous glycerol solution
specific activity11.2-16.8 nmol/min·mg
mol wt ~100 kDa
NCBI accession no.NM_011058
shipped indry ice
storage temp.−70°C
Gene Informationmouse ... Pdgfra(18595)
长度(mm)
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