Anti Dynamin 1 Antibody, clone 23GB5165, Rabbit Monoclonal,1004G,SAB6012229-100UL,Sigma

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订货号 0BQ2521
品牌型号 Sigma SAB6012229-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3′ region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
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Immunogen

A synthesized peptide corresponding to a sequence within amino acids 800-864 of human Dynamin 1 [NP_004399.2].


Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.


Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.


技术参数 Specifications
biological sourcerabbit (Monoclonal)
Quality Segment100
recombinantexpressed in HEK 293 cells
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clone 23GB5165, recombinant monoclonal
formbuffered aqueous glycerol solution
mol wt 97 kDa
species reactivityhuman
packagingvial of 1.5 mL
enhanced validationrecombinant expression
Learn more about Antibody Enhanced Validation
sustainabilityGreener Alternative Product
concentration0.5 mg/ml
technique(s)western blot: 1:1,000-1:5,000
isotypeIgG
Ensembl | human accession no.ENSG00000106976
NCBI accession no.NP_004399.2
UniProt accession no.Q05193
greener alternative categoryDfS-Developed
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... DNM1(1759)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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