Anti-Monkeypox virus/MPXV H3L Antibody (SAA0282),1MG,SAB5900401-1MG,Sigma

销售价: ¥ 12701.89 / 件
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订货号 0BQ2812
品牌型号 Sigma SAB5900401-1MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Anti-Monkeypox virus/MPXV H3L Antibody, clone SAA0282 is produced in mouse. The monoclonal antibodies are IgG immunoglobulins, which consist of two heavy chains and two light chains. Each heavy chain contains four domains, and each light chain contains two domains. The antibody binds to the antigen of the monkeypox virus, which is the H3L protein.




Monkeypox virus (MPXV), like smallpox virus, belongs to the genus Orthopoxvirus. Its morphology is consistent with that of orthopoxvirus, with a brick-shaped or oval shape with rounded corners and a size of 200~400nm. Brick-shaped or oval-shaped, covered by a lipoprotein membrane or envelope, with two protein-containing side bodies in the middle, and a thick membrane core containing a large double-stranded DNA gene body. The genome of Mpox virus is a double-stranded DNA, about 197kb long, and the end of the genome contains an identical but opposite terminal inverted repeat sequence. The virus contains 190 open reading frames, 4 of which are located in terminal inverted repeats. The core proteins of monkeypox virus are A29L, A35R, B6R, M1R, H3L.


Application

ELISA,neutralization


Biochem/physiol Actions

Monoclonal Anti-Monkeypox virus/MPXV H3L Antibody, clone SAA0282 is highly specific and bind to the H3L protein of the virus. This binding inhibits the virus from entering cells, thus preventing infection. The antibodies also trigger the body’s immune system to produce anti-viral proteins that can clear the virus from the body.


Packaging

100µg per vial / 1 mg per vial


Preparation Note

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.


技术参数 Specifications
biological sourcemouse
Quality Segment100
recombinantexpressed in CHO cells
conjugateunconjugated
antibody formaffinity purified immunoglobulin
cloneSAA0282, recombinant monoclonal
assay>95% (SDS-PAGE)
formliquid
mol wt 150 kDa
species reactivitymonkeypox virus
concentration1 mg/mL
technique(s)ELISA: 1:2000-1:4000,neutralization: 0.01-10 μg/mL
color colorless
pH7.4
isotypeIgG2a, kappa
Protein ID accession no.NP_536520.1
UniProt accession no.Q8V4Z2
shipped inwet ice
storage temp.-65 to -96°C
target post-translational modificationunmodified
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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