IgG2a, Kappa from murine myeloma,5MG,M7769-5MG,Sigma

销售价: ¥ 3971.76 / 件
在线询价
优    惠: 请询价
订货号 0BQ3808
品牌型号 Sigma M7769-5MG
货期 询货期
最小订货量 1件
联系我们
  • 400-920-3909
微信扫一扫,手机采购
  • 商品介绍
  • 规格参数
  • 包装参数
产品介绍 Product Description

General description

The UPC-10 tumor line that produces mouse IgG2a, K is a tetramethylpentadecane (pristane) induced plasmacytoma originated and carried intraperitoneally in BALB/c mice. The hapten binding specificity of the UPC-10 line is for β-2-6-linked fructosan. The ascites produced from the UPC-10 tumor line contains IgG2a, K in addition to normal levels of other mouse immunoglobulins and serum proteins. The ascites fluid is clarified by centrifugation and filtration. IgG2a (immunoglobulin G 2a) is one of the subclasses of rat immunoglobulins, which also include IgG1, IgG2b and IgG2c.


Immunogen

The UPC-10 tumor line that produces mouse IgG2a, K is a tetramethylpentadecane (pristane) induced plasmacytoma originated and carried intraperitoneally in BALB/c mice.


Application

IgG2a, Kappa from murine myeloma has been used in immunofluorescence and immunohistochemistry.


Biochem/physiol Actions

The IgG2a (immunoglobulin G 2a) plays a vital role in stimulating autoimmunity in mice. This gene is expressed at high level during virus infection. IgG2a offers host defence through activation of complement system. This antibody has specificity towards Fc receptors expressed on phagocytes and stimulates antibody-dependent cell mediated cytotoxicity. IgG2a also induces macrophage-mediated opsonophagocytosis, which has been observed in response to influenza virus and leads to its clearance from the infected cells.
Antigen Specificity: β-2,6-fructosan

Trace amounts of lambda chain may be present.


Physical form

The product provided is lyophilized from 0.01 M phosphate buffered saline, pH 7.2, with no preservatives added.


Preparation Note

Storage and Stability: Store the product at 2-8 °C. After reconstitution, the solution may be stored frozen in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage clarify the solution by centrifugation before use.


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcemouse
Quality Segment300
conjugateunconjugated
antibody formascites fluid
cloneUPC 10, monoclonal
formlyophilized powder
storage temp.2-8°C
target post-translational modificationunmodified
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
猜你喜欢

在线
客服

在线客服服务时间:09:00-18:00

微信扫码咨询

客服
热线

400-920-3909
客服服务热线 周一至周五(09:00-18:00)

微信
咨询

微信小程序 7X24小时在线咨询