Anti-PKR/EIF2AK2 Antibody, clone 5B7B6, Rabbit Monoclonal,100UL,SAB5702216-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BQ4322
品牌型号 Sigma SAB5702216-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 450-551 of human PKR/EIF2AK2 (P19525).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


Application

WB


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
materialcolorless
clone5B7B6, monoclonal
formliquid
mol wt 70 kDa
species reactivityrat, human
concentration0.29 mg/mL
technique(s)western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceGTLRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWKKSPEKNERHTC
UniProt accession no.P19525
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... EIF2AK2(5610)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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