Anti-phospho-EIF2S1 (pSer⁵¹) antibody produced in rabbit，100UG，SAB4300221-100UG，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.

Immunogen

Peptide sequence around phosphorylation site of serine 51 (E-L-S(p)-R-R), according to the protein EIF2S1.

Features and Benefits

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Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

技术参数 Specifications

biological source	rabbit
Quality Level	100
conjugate	unconjugated
antibody form	affinity isolated antibody
antibody product type	primary antibodies
clone	polyclonal
form	buffered aqueous solution
mol wt	~38 kDa
species reactivity	rat, mouse, human
concentration	1 mg/mL
technique(s)	immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100,indirect immunofluorescence: 1:100-1:200,western blot: 1:500-1:1000
isotype	IgG
immunogen sequence	(E-L-SP-R-R)
NCBI accession no.	NP_004085.1
UniProt accession no.	P05198
shipped in	wet ice
storage temp.	−20°C
target post-translational modification	phosphorylation (pSer51)
Gene Information	human ... EIF2S1(1965)

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