- 商品介绍
- 规格参数
- 包装参数
General description
Chromogranin A (CgA) is a circulating protein liberated by the neuroendocrine system. It is a glycoprotein that is located on human chromosome 14.
Chromogranin A (a protein of 439 amino acid which is encoded on chromosome 14) is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, phenochromocytomas, paragangliomas, and other neuroendocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.
Immunogen
Recombinant protein encoding human chromogranin A.
Biochem/physiol Actions
Chromogranin A (CgA) controls vascular physiology and angiogenesis. It modulates the storage and liberation of catecholamine via intracellular (vesiculogenic) and extracellular (catecholamine release–inhibitory) mechanisms. CHGA is essential to generate catecholamine secretory vesicles in chromaffin-lineage PC12 cells and is required to promote a regulated secretion system in nonsecretory cells.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
0.1 ml rabbit monoclonal antibody supplied as tissue culture supernatant in TBS/1% BSA buffer pH 7.5 with less than 0.1% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| recombinant | expressed in proprietary host |
| conjugate | unconjugated |
| antibody form | tissue culture supernatant |
| antibody product type | primary antibodies |
| clone | SP12, monoclonal |
| species reactivity | human (tested) |
| species reactivity (predicted by homology) | bovine, pig |
| technique(s) | immunohistochemistry: 1:200 |
| isotype | IgG |
| UniProt accession no. | P10645 |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| Gene Information | human ... CHGA(1113) |
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¥ 6894.69
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¥ 9737.84
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¥ 4968.78
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¥ 4390.38
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瓶顶过滤器-500ml容量,MF75TM系列，聚苯乙烯外壳，75mmPES滤膜，孔径0.45um,适合瓶颈尺寸33mm，12/箱，295-3345，Nalgene，Thermofisher，赛默飞世尔¥ 1938.54
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¥ 3852.13
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¥ 1196.14
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¥ 954.17
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