- 商品介绍
- 规格参数
- 包装参数
General description
gp120 Antibody: Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.
Immunogen
gp120 antibody was raised against 16 amino acid synthetic peptide representing the major HIV-1 consensus sequence near the N-terminal region of V1/V2 loop.The immunogen is located within amino acids 80 - 130 of gp120.
Application
Gp120 antibody can be used for detection of gp120 by Western blot at 1 μg/mL.
Physical form
Supplied in PBS containing 0.02% sodium azide.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | liquid |
| species reactivity | human immunodeficiency virus 1 |
| concentration | 1 mg/mL |
| technique(s) | western blot: suitable |
| isotype | IgG |
| UniProt accession no. | Q6BBS3 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human immunodeficiency virus 1 ... env(155971) |
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¥ 2622.09
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¥ 1259.40
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