- 商品介绍
- 规格参数
- 包装参数
General description
NIMA-related Kinase 7/never in mitosis A-related kinase 7 (NEK7), a serine/threonine kinase belongs to the NIMA-related protein kinase (NEK) family. It is the smallest NIMA-related kinase (NEK) protein seen in mammals, which is made up of a catalytic domain with a 30–40 amino acid N-terminal extension. NEK7 is abundantly expressed in the heart, liver, testis, lung, muscle, brain, spleen, and leukocyte. The NEK7 gene is located on human chromosome 1.
Immunogen
The antiserum was produced against synthesized peptide derived from human NEK7.
Immunogen Range: 101-150
Biochem/physiol Actions
NIMA-related Kinase 7/never in mitosis A-related kinase 7 (NEK7) is essential to form procentriole. It participates in regulating the cell cycle. In addition to the pathological and physiological effects, NEK7 is also involved in the formation of the spindle during mitosis. It is expressed at a high level in gallbladder cancer. NEK7 controls cytokinesis and stability of the microtubule. It can activate the spindle assembly checkpoint. NEK7 might also be associated with hepatocellular carcinoma (HCC).
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | antigen 34 kDa |
| species reactivity | human, mouse |
| concentration | ~1 mg/mL |
| technique(s) | ELISA: 1:40000,immunohistochemistry: 1:50-1:100,western blot: 1:500-1:1000 |
| NCBI accession no. | Q8TDX7 |
| UniProt accession no. | Q8TDX7 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... NEK7(140609) |
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