- 商品介绍
- 规格参数
- 包装参数
General description
Tet methylcytosine dioxygenase 2 (TET2) is part of the Fe(II)/α-ketoglutarate-dependent dioxygenase family of enzymes. It is expressed in the brain. The gene encoding TET2 is localized on human chromosome 4q24.
Immunogen
Antibody was raised against an 18 amino acid peptide near the amino terminus of human TET2.
Application
Anti-TET2 antibody produced in rabbit has been used in Western blotting.
Biochem/physiol Actions
Tet methylcytosine dioxygenase 2 (TET2) is involved in the conversion of 5-methylcytosine to 5-hydroxymethyl-cytosine (5hmC). It also has a role in stimulating DNA demethylation and lymphomagenesis. Mutations in the gene encoding TET2 have been linked to myelodysplastic syndromes.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied at 1 mg/mL in PBS with 0.02% sodium azide.
Other Notes
The action of this antibody can be blocked using blocking peptide SBP3500711.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| mol wt | 220 kDa |
| species reactivity | human |
| concentration | 1 mg/mL |
| technique(s) | ELISA: suitable,western blot: suitable |
| NCBI accession no. | NP_001120680 |
| UniProt accession no. | Q6N021 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... TET2(54790) |
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