Monoclonal Anti-HMGA2 antibody produced in mouse,100UG,WH0008091M1-100UG,Sigma

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订货号 0BQ9941
品牌型号 Sigma WH0008091M1-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. (provided by RefSeq)


Immunogen

HMGA2 (NP_003474, 1 a.a. ~ 92 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAAQKKAEATGEKRPRGRPRKWPQQVVQKKP


Physical form

Solution in phosphate buffered saline, pH 7.4


Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone2D10, monoclonal
formbuffered aqueous solution
species reactivityhuman
technique(s)immunofluorescence: suitable,indirect ELISA: suitable,western blot: 1-5 μg/mL
isotypeIgG1κ
GenBank accession no.NM_003483
UniProt accession no.P52926
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... HMGA2(8091)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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