Anti-CNPase antibody produced in rabbit,100UG,C9743-100UG,Sigma

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订货号 0BR0763
品牌型号 Sigma C9743-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Immunogen

synthetic peptide corresponding to residues 122-136 of human CNPase. The sequence is 93% identical in mouse and rat.


Application

Anti-CNPase antibody produced in rabbit is suitable for flow cytometry at a working dilution of 1:200-1:500, immunohistochemistry at 1:100-1:200 and western blotting at 1:500-1:1000. It was used at a working dilution of 1:1000 as a primary antibody in western blotting of cerebrospinal fluid samples in a study.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)


Biochem/physiol Actions

CNPase (2′,3′-cyclic nucleotide 3′-phosphodiesterase) is associated with brain tubulin and acts as a microtubule-associated protein in promoting microtubule assembly and distribution. It is expressed primarily in committed oligodendroglial progenitors and terminally-differentiated oligodendrocytes and may be used as a marker of cell differentiation in the CNS.


Physical form

solution in phosphate buffered saline, containing 0.02% sodium azide.


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcerabbit
Quality Segment200
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wtantigen 46-48 kDa
species reactivityhuman, mouse, rat
concentration~1 mg/mL
technique(s)flow cytometry: 1:200-1:500,immunohistochemistry: 1:100-1:200,western blot: 1:500-1:1,000
UniProt accession no.P09543
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... CNP(1267)
mouse ... Cnp(12799)
rat ... Cnp(25275)
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