- 商品介绍
- 规格参数
- 包装参数
General description
Mutations in p95/NBS1 gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
Immunogen
Peptide sequence around aa. 341-345 (S-L-S-Q-G), according to the protein NBN.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | ~95 kDa |
| species reactivity | human |
| concentration | 1 mg/mL |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100,western blot: 1:500-1:1000 |
| isotype | IgG |
| immunogen sequence | (S-L-S-Q-G) |
| NCBI accession no. | NP_002476.2 |
| UniProt accession no. | O60934 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... NBN(4683) |
| 长度(mm) | |
| 宽度(mm) | |
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