KD-Validated Anti ATP7B Antibody, clone 23GB3945, Rabbit Monoclonal，1004G，SAB6012335-100UL，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein is a monomer, and functions as a copper-transporting ATPase which exports copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease which is characterized by copper accumulation. [provided by RefSeq, Dec 2019]
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Immunogen

A synthesized peptide corresponding to a sequence within amino acids 1400-1465 of human ATP7b [NP_000044.2].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

技术参数 Specifications

biological source	rabbit (Monoclonal)
Quality Segment	100
recombinant	expressed in HEK 293 cells
conjugate	unconjugated
antibody form	affinity isolated antibody
antibody product type	primary antibodies
clone	23GB3945, recombinant monoclonal
form	buffered aqueous glycerol solution
mol wt	157 kDa
species reactivity	human
packaging	vial of 1.5 mL
enhanced validation	recombinant expression Learn more about Antibody Enhanced Validation
sustainability	Greener Alternative Product
concentration	0.46 mg/ml
technique(s)	flow cytometry: 1:2000,immunofluorescence: 1:100-:1000,western blot: 1:1,000-1:5,000
isotype	IgG
Ensembl \| human accession no.	ENSG00000123191
NCBI accession no.	NP_000044.2
UniProt accession no.	P35670
greener alternative category	DfS-Developed
shipped in	wet ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... ATP7B(540)

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