- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
SGK1 is a member of the serum- and glucocorticoid-induced protein kinase that is activated in vitro by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and in vivo in response to signals that activate phosphatidylinositol (PI) 3-kinase. SGK1 mRNA is expressed in all tissues and the level of SGK1 mRNA is increased by stimulation with serum or dexamethasone. SGK1 promotes cell survival by phosphorylating and inactivating FKHRL1. SGK and Akt display differences with respect to the efficacy with which they phosphorylate the three regulatory sites on FKHRL1.
Physical form
Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
Legal Information
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
| recombinant | expressed in baculovirus infected Sf9 cells |
| Quality Level | 200 |
| product line | PRECISIO® Kinase |
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| specific activity | 99-135 nmol/min·mg |
| mol wt | ~73 kDa |
| UniProt accession no. | O00141 |
| shipped in | dry ice |
| storage temp. | −70°C |
| Gene Information | human ... SGK1(6446) |
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| 重量(kg) |
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¥ 2707.32
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¥ 1148.92
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¥ 2290.21
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¥ 1302.89
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¥ 2019.57
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¥ 15214.65
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¥ 37675.92
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