Anti-STAT4 Antibody, clone 10H10O9, Rabbit Monoclonal,100UL,SAB5702484-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BR3618
品牌型号 Sigma SAB5702484-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 649-748 of human STAT4 (Q14765).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


Application

WB, IF/ICC, IP


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
materialcolorless
clone10H10O9, monoclonal
formliquid
mol wt 86 kDa
species reactivityrat, human
concentration1.05 mg/mL
technique(s)immunofluorescence: 1:50 - 1:200,immunoprecipitation (IP): 1:50 - 1:200,western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceMAENIPENPLKYLYPDIPKDKAFGKHYSSQPCEVSRPTERGDKGYVPSVFIPISTIRSDSTEPHSPSDLLPMSPSVYAVLRENLSPTTIETAMKSPYSAE
UniProt accession no.Q14765
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... STAT4(6775)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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