Anti-MMP7 Antibody, clone 9D8S10, Rabbit Monoclonal,100UL,SAB5702262-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BR3693
品牌型号 Sigma SAB5702262-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers.


Immunogen

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Recombinant protein of human MMP7.


Application

WB, IHC


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
materialcolorless
clone9D8S10, monoclonal
formliquid
species reactivityhuman, rat
concentration4.84 mg/mL
technique(s)immunohistochemistry: 1:50 - 1:200,western blot: 1:500 - 1:2000
color colorless
isotypeIgG
UniProt accession no.P09237
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... MMP7(4316)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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