Anti-S100B antibody produced in rabbit,100UL,SAB5700647-100UL,Sigma

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订货号 0BR5337
品牌型号 Sigma SAB5700647-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer′s disease, Down′s syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.


Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human S100B (NP_006263.1).


Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.


Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.


技术参数 Specifications
biological sourcerabbit
Quality Level100
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wt 10
species reactivityrat, mouse, human
concentration2.8 mg/ml
technique(s)immunofluorescence: 1:50-1:200,immunohistochemistry: 1:50-1:200,western blot: 1:500-1:2000
UniProt accession no.P04271
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... S100B(6285)
长度(mm)
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高度(mm)
重量(kg)
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