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Biochem/physiol Actions
Exhibits activity on eosinophils, B cells, and thymocytes.
Interleukin-5 exhibits activity on eosinophils, B cells, and thymocytes. Human and mouse IL-5 exhibit homology at the nucleotide and amino acid levels and show species cross-reactivity.
Interleukin-5 is a product of activated T lymphocytes and exhibits activity on eosinophils, B cells and thymocytes. Synonyms or biological activities attributed to IL-5 include: EDF (eosinophil differentiating factor), BCGF-II (B cell growth factor-II), TRF (T cell replacing factor), IgA-EF (IgA enhancing factor) and EO-CSF (eosinophil colony stimulating factor). Natural IL-5 is a 45-50 kDa dimeric glycoprotein, although glycosylation is not required for activity. Human and mouse IL-5 exhibit homology at the nucleotide and amino acid levels and show species cross-reactivity.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.25 mg bovine serum albumin.
| biological source | mouse |
| Quality Segment | 200 |
| recombinant | expressed in baculovirus infected Sf21 cells |
| assay | ≥97% (SDS-PAGE) |
| form | lyophilized powder |
| potency | 0.04-0.30 ng/mL EC50 |
| mol wt | 45-50 kDa |
| packaging | pkg of 5 μg |
| technique(s) | cell culture | mammalian: suitable |
| impurities | endotoxin, tested |
| UniProt accession no. | P04401 |
| storage temp. | −20°C |
| Gene Information | mouse ... Il5(16191) |
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NNALGENE 180透明塑料管，透明，柔软，多用，经济，内径 x 外径x壁厚，1/4 x 1/2 x 1/8，英寸，每箱数量50，50/箱，8000-0080，Thermofisher，赛默飞世尔
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