Anti-COL1A1 antibody produced in rabbit,100UL,SAB5700733-100UL,Sigma

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订货号 0BR5720
品牌型号 Sigma SAB5700733-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human COL1A1 (NP_000079.2).


Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.


Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.


技术参数 Specifications
biological sourcerabbit
Quality Level100
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wt 138
species reactivitymouse, rat, human
concentration2.67 mg/ml
technique(s)immunofluorescence: 1:50-1:200,immunohistochemistry: 1:50-1:200,immunoprecipitation (IP): 1:50-1:200,western blot: 1:500-1:1000
UniProt accession no.P02452
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... COL1A1(1277)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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