抗-CCR7 兔抗,100UG,SAB4300627-100UG,Sigma

销售价: ¥ 4320.72 / 件
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订货号 0BR5772
品牌型号 Sigma SAB4300627-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Anti-CCR7 antibody detects endogenous level of total CCR7(CD197) protein. CCR7 (C-C motif chemokine receptor 7) is localized to T cells, natural killer and dendritic cells. The CCR7 gene is mapped to human chromosome 17q21.2.
Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.


Immunogen

Peptide sequence around aa. 29-33 (T-D-D-Y-I), according to the protein NP_001829.1


Biochem/physiol Actions

CCR7 (C-C motif chemokine receptor 7) regulates lymphocyte cell trafficking and lymph node distribution. CCR7′s interaction with CCL21 promotes metastasis of cancer via lymph node. CCR7 is known to be associated with breast cancer, melanoma, colorectal cancer, non-small cell lung cancer, and chronic lymphocytic leukemia.


Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.


Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wt ~43 kDa
species reactivityhuman
concentration1 mg/mL
technique(s)western blot: 1:500-1:1000
isotypeIgG
immunogen sequence(T-D-D-Y-I)
NCBI accession no.NM_001838.3
UniProt accession no.P32248
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... CCR7(1236)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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