Anti-Thyroid Peroxidase Antibody, clone 3C4A4, Rabbit Monoclonal,100UL,SAB5702178-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BR6479
品牌型号 Sigma SAB5702178-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Thyroid Peroxidase (P07202).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


Application

IHC


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
materialcolorless
clone3C4A4, monoclonal
formliquid
species reactivityhuman, rat
concentration1.09 mg/mL
technique(s)immunohistochemistry: 1:50 - 1:200
color colorless
isotypeIgG
immunogen sequenceMRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQRNLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQA
UniProt accession no.P07202
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... TPO(7173)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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