Anti-TMEM123 antibody produced in mouse,50UG,SAB1408843-50UG,Sigma

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订货号 0BR6511
品牌型号 Sigma SAB1408843-50UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. (provided by RefSeq)


Immunogen

TMEM123 (NP_443164.2, 1 a.a. ~ 208 a.a) full-length human protein.

Sequence
MGLGARGAWAALLLGTLQVLALLGAAHESAAMAASANIENSGLPHNSSANSTETLQHVPSDHTNETSNSTVKPPTSVASDSSNTTVTTMKPTAASNTTTPGMVSTNMTSTTLKSTPKTTSVSQNTSQISTSTMTVTHNSSVTSAASSVTITTTMHSEAKKGSKFDTGSFVGGIVLTLGVLSILYIGCKMYYSRRGIRYRTIDEHDAII


Physical form

Solution in phosphate buffered saline, pH 7.4


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wtantigen 21.5 kDa
species reactivityhuman
technique(s)western blot: 1 μg/mL
NCBI accession no.NM_052932.2
UniProt accession no.Q8N131
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... TMEM123(114908)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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