- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
Biochem/physiol Actions
Cell penetrant, potent and selective ATP-competitive antagonist of both the kinase and RNase activities of IRE1α
KIRA9 is a cell penetrant, potent and selective ATP-competitive antagonist of both the kinase and RNase activities of IRE1α (endoplasmic reticulum to nucleus signaling 1). KIRA9 suppresses destructive ER mRNA endonucleolytic decay and apoptosis.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | O=S(NC(C=C1)=C2C(C=CC=C2)=C1OC3=NC=CC=C3C4=CC=NC(N[C@@H]5CNCCC5)=N4)(CCC(F)(F)F)=O |
| InChI | 1S/C27H27F3N6O3S/c28-27(29,30)12-16-40(37,38)36-23-9-10-24(20-7-2-1-6-19(20)23)39-25-21(8-4-14-32-25)22-11-15-33-26(35-22)34-18-5-3-13-31-17-18/h1-2,4,6-11,14-15,18,31,36H,3,5,12-13,16-17H2,(H,33,34,35)/t18-/m0/s1 |
| InChI key | HLEZGQAFDDCWDE-SFHVURJKSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
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