- 商品介绍
- 规格参数
- 包装参数
General description
Discovered in the 1970s, m6A is the most prevalent internal modification in polyadenylated mRNAs and long non-coding RNAs (lncRNAs) in higher eukaryotes. m6A is widely conserved among eukaryotic species that range from yeast, plants, flies to mammals, as well as among viral RNAs with a nuclear phase. The m6A-based modification is associated with a well-defined RNA motif, RRACH (R: A/G, H: A/C/U). As a representative of the epitranscriptome, m6A mRNA modifications participate in many vital activities in the cell, including stem cell self-renewal and differentiation, mRNA transcription, alternative splicing, nuclear export, translation, degradation, and microRNA processing. These processes determine the expression or inactivation of specific genes, which is vital for growth and development.(PMID: 30416848; PMID: 24662220; PMID: 30429466)
Immunogen
Chemical compounds corresponding to N6-methyladenosine / m6A.
Physical form
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
| biological source | rabbit |
| Quality Segment | 100 |
| antibody product type | primary antibodies |
| clone | monoclonal |
| form | liquid |
| species reactivity | rat, human, mouse |
| concentration | 1 mg/mL |
| technique(s) | immunohistochemistry: 1:50-1:200,western blot: 1:500-1:2000 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| 长度(mm) | |
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| 重量(kg) |
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¥ 2622.09
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¥ 9207.92
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¥ 3442.25
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¥ 4404.38
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¥ 8982.64
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¥ 1476.00
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¥ 1564.00
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¥ 1301.36
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¥ 2888.88
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¥ 66743.99
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¥ 165230.53
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¥ 29754.56
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