Anti-CISH antibody produced in mouse,50UG,SAB1400049-50UG,Sigma

销售价: ¥ 4585.89 / 件
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订货号 0BR8026
品牌型号 Sigma SAB1400049-50UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)


Immunogen

CISH (NP_659508.1, 1 a.a. ~ 258 a.a) full-length human protein.

Sequence
MVLCVQGPRPLLAVERTGQRPLWAPSLELPKPVMQPLPAGAFLEEVAEGTPAQTESEPKVLDPEEDLLCIAKTFSYLRESGWYWGSITASEARQHLQKMPEGTFLVRDSTHPSYLFTLSVKTTRGPTNVRIEYADSSFRLDSNCLSRPRILAFPDVVSLVQHYVASCTADTRSDSPDPAPTPALPMPKEDAPSDPALPAPPPATAVHLKLVQPFVRRSSARSLQHLCRLVINRLVADVDCLPLPRRMADYLRQYPFQL


Physical form

Solution in phosphate buffered saline, pH 7.4


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formIgG fraction of antiserum
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
species reactivityhuman
technique(s)indirect immunofluorescence: suitable,western blot: 1 μg/mL
UniProt accession no.Q9NSE2
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... CISH(1154)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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