- 商品介绍
- 规格参数
- 包装参数
General description
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
Immunogen
A synthesized peptide derived from human Phospho-MLKL (S358)
Physical form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Preparation Note
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Other Notes
344-389aa
| recombinant | expressed in HEK 293 F cells |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody product type | primary antibodies |
| clone | 4A6, recombinant monoclonal |
| form | liquid |
| mol wt | 150 kDa |
| purified by | affinity chromatography |
| species reactivity | human |
| concentration | 1.6mg/ml |
| technique(s) | ELISA: 2000:10000,flow cytometry: 1:50-1:200,immunofluorescence: 1:50-1:200,immunohistochemistry: 1:50-1:200 |
| isotype | IgG |
| UniProt accession no. | Q8NB16 |
| shipped in | wet ice |
| storage temp. | -10 to -25°C |
| target post-translational modification | phosphorylation (pSer358) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
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¥ 1573.49
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¥ 5725.45
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¥ 1749.15
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¥ 39676.71
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