- 商品介绍
- 规格参数
- 包装参数
General description
Anti-ARHGEF10 Antibody detects endogenous levels of total ARHGEF10 protein.
The gene ARHGEF10 (Rho guanine nucleotide exchange factor 10) is mapped to human chromosome 8p23. It belongs to the Rho-specific guanine nucleotide exchange factor family. The protein contains tandem Dbl homology (DH) domain, pleckstrin homology (PH) domain and putative transmembrane domains.
Immunogen
The antiserum was produced against synthesized peptide derived from human ARHGEF10.
Immunogen Range: 339-388
Biochem/physiol Actions
ARHGEF10 (Rho guanine nucleotide exchange factor 10) works as a guanine nucleotide exchange factor for RhoA, RhoB and RhoC. It is involved in atherosclerotic cerebral infarction and mutation in ARHGEF10 is associated with increased risk of atherothrombotic stroke. Mutation in ARFGEF10 is also linked with slowed nerve conduction velocities and thin myelination of peripheral nerves.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | antigen 151 kDa |
| species reactivity | human |
| concentration | ~1 mg/mL |
| technique(s) | ELISA: 1:20000,immunohistochemistry: 1:50-1:100,western blot: 1:500-1:1000 |
| NCBI accession no. | O15013 |
| UniProt accession no. | O15013 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... ARHGEF10(9639) |
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¥ 2814.26
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¥ 2013.69
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¥ 4173.75
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¥ 3372.68
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¥ 5167.58
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¥ 2151.46
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¥ 1196.00
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¥ 5014.59
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¥ 8137.12
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¥ 1476.40
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