Monoclonal Anti-ELAC2 antibody produced in mouse,100UG,SAB1402616-100UG,Sigma

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订货号 0BR9108
品牌型号 Sigma SAB1402616-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3′ trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)


Immunogen

ELAC2 (NP_060597.3, 2 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
WALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGAALYVFSEFNRYLFNCGEGVQRLMQEHKL


Physical form

Solution in phosphate buffered saline, pH 7.4


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone1A2, monoclonal
formbuffered aqueous solution
mol wtantigen ~37 kDa
species reactivityhuman
technique(s)direct immunofluorescence: suitable,indirect ELISA: suitable
isotypeIgG2aκ
NCBI accession no.NM_018127
UniProt accession no.Q9BQ52
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... ELAC2(60528)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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