- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
MEK2 is the member of MAPK kinase (MAPKK) family of signaling protein kinases. MEK2 is a dual-specificity kinase that activates the extracellular signal-regulated kinase (ERK) and mitogen-activated protein (MAP) kinase upon agonist binding to receptors. MEK2 plays a key role in the Ras/Raf/MEK/ERK mitogen-activated protein kinase (MAPK) signaling pathways. Approximately 30% of all human cancers have a constitutively activated MAPK pathway, and constitutive activation of MEK2 results in cellular transformation. The ERK/MAP kinase cascade regulates cell growth and differentiation.
Physical form
Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
Legal Information
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
| recombinant | expressed in baculovirus infected Sf9 cells |
| Quality Segment | 200 |
| product line | PRECISIO® Kinase |
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| specific activity | 190-258 nmol/min·mg |
| mol wt | ~71 kDa |
| UniProt accession no. | P36507 |
| shipped in | dry ice |
| storage temp. | −70°C |
| Gene Information | human ... MAP2K2(5605) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
询价
-
¥ 2290.21
-
¥ 1451.54
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
¥ 6894.69
-
询价
-
¥ 238.17
-
¥ 4390.38
-
¥ 1568.60
-
¥ 2617.87
-
¥ 1301.36
-
¥ 3852.13
-
¥ 1196.14
-
¥ 5061.38
-
¥ 3662.39
微信小程序
7X24小时在线咨询