Monoclonal Anti-ADAMTS17 antibody produced in mouse,100UG,WH0170691M1-100UG,Sigma

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订货号 0BR9686
品牌型号 Sigma WH0170691M1-100UG
货期 询货期
最小订货量 1件
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实验室两箱一柜(超低温冰箱、培养箱、生物安全柜)、离心机
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产品介绍 Product Description

General description

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by ADAMTS19, another family member. The function of this protein has not been determined. (provided by RefSeq)


Immunogen

ADAMTS17 (NP_620688, 543 a.a. ~ 650 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
DGDWSPWGAWSMCSRTCGTGARFRQRKCDNPPPGPGGTHCPGASVEHAVCENLPCPKGLPSFRDQQCQAHDRLSPKKKGLLTAVVVDDKPCELYCSPLGKESPLLVAD


Biochem/physiol Actions

ADAM metallopeptidase with thrombospondin type 1 motif 17 (ADAMTS17) is associated with Weill-Marchesani-like syndrome. Knockdown of the protein has been shown to prevent the growth of breast cancer cells in vitro. ADAMTS17 binds to the extracellular matrix.


Physical form

Solution in phosphate buffered saline, pH 7.4


Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone3B7, monoclonal
formbuffered aqueous solution
species reactivityhuman, mouse, rat
technique(s)indirect ELISA: suitable,western blot: 1-5 μg/mL
isotypeIgG1κ
GenBank accession no.NM_139057
UniProt accession no.Q8TE56
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... ADAMTS17(170691)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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