- 商品介绍
- 规格参数
- 包装参数
General description
Currently, there are 13 caspases recognized in mammals. Caspases are classified as initiators and effectors. Caspase 8 belongs to the class of initiators. It possesses a prodomain at the terminal and contains the death effector domain which serves as protein-protein interaction motif for caspase 8. With respect to substrate specificity, caspase 8 is classified as a member of group III. It specifically recognizes the (I/L/V) EXD sequence on the substrate.
Application
Caspase Inhibitor has been used to study the specificity of the CIL-1 (desglucoanagalloside B) interaction with the caspase 3/7 system.
Biochem/physiol Actions
The peptide Ac-Ala-Glu-Val-Asp-al, or Ac-AEVD-CHO, is an inhibitor of Group III caspases. It acts upon caspases-6, 8, 9, and 10, with particular effectiveness on caspase-6 and caspase-8. The use of Ac-AEVD-CHO in several apotosis studies has been reported.
| assay | ≥95% (HPLC) |
| form | lyophilized |
| composition | Peptide Content, ≥80% |
| storage condition | protect from light |
| storage temp. | −20°C |
| Gene Information | human ... CASP10(843), CASP6(839), CASP8(841), CASP9(842) |
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¥ 2814.26
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¥ 1779.22
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¥ 8520.40
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¥ 3152.47
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¥ 6330.00
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瓶顶过滤器-500ml容量,MF75TM系列，聚苯乙烯外壳，75mmSFCA滤膜，孔径0.2um,适合瓶颈尺寸45mm，12/箱，291-4520，Nalgene，Thermofisher，赛默飞世尔¥ 2856.42
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无菌，PETG 方形有刻度培养基瓶，带盖，聚对苯二酸乙二醇酯共聚物，天然高密度聚乙烯盖，500毫升容量，每箱40，40/箱，342020-0500，Nalgene，Thermofisher，赛默飞世尔¥ 3684.34
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¥ 2666.57
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¥ 1156.91
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¥ 4011.97
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¥ 2452.91
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