- 商品介绍
- 规格参数
- 包装参数
General description
Protein tyrosine phosphatase-PEST (PTPN12), a ubiquitously expressed cytoplasmic tyrosine phosphatase, is thought to play an important role in cell adhesion and motility, cell migration, and signal transduction for antigen receptors in B and T lymphocytes. Signal transduction via tyrosine phosphorylation, normally fine-tuned by the concerted action of both protein tyrosine kinases and protein tyrosine phosphatases (PTPs), is a key mechanism in tumorigenesis. Studies suggest potential role for PTP-PEST in regulation of p130(cas) in mitogen- and cell adhesion-induced signaling events.
Physical form
Supplied in 20mM MOPS, pH 7.5, 50mM NaCl, 10mM glutathione, 0.25mM DTT, 0.1mM PMSF, 30% glycerol.
Preparation Note
after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles
| recombinant | expressed in E. coli |
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| specific activity | 2520-3410 nmol/min·mg |
| mol wt | ~66 kDa |
| NCBI accession no. | NM_002835 |
| shipped in | dry ice |
| storage temp. | −70°C |
| Gene Information | human ... PTPN12(5782) |
| 长度(mm) | |
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询价
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¥ 2622.09
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¥ 1451.54
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¥ 3109.49
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¥ 5167.58
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无菌，PETG 方形有刻度培养基瓶，带盖，聚对苯二酸乙二醇酯共聚物，天然高密度聚乙烯盖，500毫升容量，每箱40，40/箱，342020-0500，Nalgene，Thermofisher，赛默飞世尔¥ 3684.34
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¥ 1476.00
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¥ 745.60
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¥ 2288.54
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¥ 56581.65
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¥ 44224.19
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