Anti-ABCG2 antibody produced in rabbit,100UL,SAB5700094-100UL,Sigma

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订货号 0BS4566
品牌型号 Sigma SAB5700094-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.


Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 260-395 of human ABCG2 (NP_004818.2).


Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.


Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wt 67, 72
species reactivityhuman, mouse, rat
concentration3.17 mg/ml
technique(s)western blot: 1:500-1:2000
UniProt accession no.Q9UNQ0
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... ABCG2(9429)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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