- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
AURORA A belongs to a multigenic family of mitotic serine/threonine kinases which are involved in the control of chromosome segregation. AURORA A is involved in centrosome separation, duplication and maturation as well as in bipolar spindle assembly and stability. AURORA A is expressed and active at the highest level during G2-M phase of the cell cycle. Overexpression of AURORA A has been found to be correlated with the grade of various human solid tumours. Ectopic AURORA A overexpression in any culture cell line leads to polyploidy and centrosome amplification.
Physical form
Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
Legal Information
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
| recombinant | expressed in baculovirus infected Sf9 cells |
| Quality Segment | 200 |
| product line | PRECISIO® Kinase |
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| specific activity | 62-84 nmol/min·mg |
| mol wt | ~72 kDa |
| UniProt accession no. | O14965 |
| shipped in | dry ice |
| storage temp. | −70°C |
| Gene Information | human ... AURKA(6790) |
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¥ 1148.92
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¥ 2528.88
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¥ 2814.26
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¥ 3109.49
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¥ 1724.25
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¥ 3152.47
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¥ 1749.15
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¥ 2132.12
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¥ 3796.67
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¥ 39676.71
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