- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
Interleukin-2 (IL-2), a cytokine, enhances Th (T helper) cell differentiation and effector responses. In addition, it helps in immune tolerance. IL-2 binds to the high affinity receptor, formed of IL2RA (interleukin 2 receptor subunit α), IL2RB (interleukin 2 receptor subunit β) and γ-chain. Polymorphism in IL2RA is associated with multiple sclerosis. Null mutation in IL2RA results in immune dysregulation.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.25 mg bovine serum albumin.
Analysis Note
The bioactivity is measured by its ability to inhibit the IL-2-dependent proliferation of a human megakaryocytic leukemic cell line, M07e.
| biological source | human |
| Quality Segment | 200 |
| recombinant | expressed in NSO cells |
| assay | >97% (SDS-PAGE) |
| form | lyophilized powder |
| potency | 0.5-1.0 mg per mL ED50 |
| mol wt | 36 kDa by SDS-PAGE |
| packaging | pkg of 5 μg |
| impurities | endotoxin, tested |
| UniProt accession no. | P01589 |
| storage temp. | −20°C |
| Gene Information | human ... IL2RA(3559) |
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¥ 1563.36
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¥ 1866.29
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¥ 8135.09
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¥ 4404.38
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¥ 8982.64
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¥ 2666.57
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¥ 1749.15
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¥ 2277.64
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