- 商品介绍
- 规格参数
- 包装参数
General description
GABAA and GABAB receptors differ with regard to their ionic characteristics and pharmacological properties. The GABAA receptor is an ionotropic receptor that forms the GABA gated chloride channel and consists of several heterogeneous subunits with membrane recognition sites for benzodiazapenes.
Immunogen
peptide corresponding to amino acid residues 1-15 of human GABA(A) receptor α3 subunit. Identical in rat and mouse. Highly conserved (14/15 residues) in bovine.
Application
Anti-GABAA Receptor (α3 subunit) antibody produced in rabbit is suitable for immunohistochemistry at a working dilution of 1:200 using rat brain frozen sections and immunoblotting at 1:200-1:300 using rat brain membranes.
Biochem/physiol Actions
The inhibitory neurotransmitter GABA signals through two distinct types of pre- and postsynaptic receptors, GABAA and GABAB. Both GABA receptors can regulate depression of synaptic transmission and be involved in the inhibition controlling neuronal excitability. α3 is a subtype of GABAA receptor expressed selectively by serotonergic and GABAergic neurons. Serotonergic neurons express strong α3 immunoreactivity but, do not show any α1 immunoreactivity. On the contrary, GABAergic neurons express both α1 and α3 subunits.
Physical form
Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, 5% sucrose and 0.025% sodium azide
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | lyophilized powder |
| species reactivity | rat |
| technique(s) | immunohistochemistry: 1:200 using Rat brain frozen sections,western blot: 1:200-1:300 using Rat brain membranes |
| UniProt accession no. | P20236 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... GABRA3(2556) mouse ... Gabra3(14396) rat ... Gabra3(24947) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
询价
-
询价
-
¥ 2290.21
-
¥ 2814.26
-
¥ 1259.40
-
¥ 8293.41
-
¥ 5887.85
-
询价
-
询价
-
¥ 1724.25
-
¥ 3152.47
-
询价
-
询价
-
询价
-
询价
-
¥ 4968.78
-
询价
-
¥ 2268.97
-
¥ 4020.77
-
¥ 2406.69
微信小程序
7X24小时在线咨询