Anti-Phospho-AMPKα1-S485 antibody produced in rabbit,100UL,SAB5701806-100UL,Sigma

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订货号 0BT1266
品牌型号 Sigma SAB5701806-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.


Immunogen

A phospho specific peptide corresponding to residues surrounding S485 of human PRKAA1


Physical form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
antibody product typeprimary antibodies
clonepolyclonal
formliquid
species reactivityhuman, mouse, rat
concentration0.91 mg/mL
technique(s)immunohistochemistry: 1:50-1:200,western blot: 1:500-1:2000
UniProt accession no.Q13131
shipped inwet ice
storage temp.−20°C
target post-translational modificationphosphorylation (pSer485)
Gene Informationhuman ... PRKAA1(5562)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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