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General description
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer′s disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Immunogen
A phospho specific peptide corresponding to residues surrounding T514 of human DPYSL2
Physical form
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Preparation Note
Store at -20℃. Avoid freeze / thaw cycles.
| biological source | rabbit |
| Quality Segment | 100 |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 58, 62 |
| species reactivity | rat, human, mouse |
| concentration | 2.63 mg/ml |
| technique(s) | western blot: 1:500-1:2000 |
| UniProt accession no. | Q16555 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pThr514) |
| Gene Information | human ... DPYSL2(1808) |
| 长度(mm) | |
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¥ 1451.54
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¥ 1724.25
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¥ 3372.68
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¥ 2307.00
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