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General description
This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants.
Immunogen
A phospho specific peptide corresponding to residues surrounding Y1022/1023 of human JAK1
Physical form
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Preparation Note
Store at -20℃. Avoid freeze / thaw cycles.
| biological source | rabbit |
| Quality Segment | 100 |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 133 |
| species reactivity | human, mouse |
| concentration | 3.16 mg/ml |
| technique(s) | immunofluorescence: 1:50-1:200,western blot: 1:500-1:2000 |
| UniProt accession no. | P23458 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pTyr1022/pTyr1023) |
| Gene Information | human ... JAK1(3716) |
| 长度(mm) | |
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¥ 4164.19
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¥ 2622.09
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¥ 1302.89
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