- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
Steroid receptor coactivator 1 (SRC1) is a transcriptional coactivoator that mediates the activating functions of many of the nuclear hormone receptors. It is also known as NCoA1 and is a member of the SRC/p160 coactivator family. SRC1 has been shown to be over expressed in some cancers. SRC1 is a 160 kDa protein that contains several LXXLL motifs, which are involved in nuclear receptor interaction. The region 627-786 contains 3 LXXLL motifs that are involved in interaction with nuclear hormone receptorsand has been previously used in assays detecting ligand-dependent receptor-cofactor interactions. This protein does not contain any tag and will be useful for assays where a native untagged protein is desired.
Physical form
Clear and colorless frozen liquid solution
Preparation Note
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.
| biological source | human |
| recombinant | expressed in E. coli |
| assay | ≥80% (SDS-PAGE) |
| form | frozen liquid |
| mol wt | ~22 kDa |
| packaging | pkg of 10 μg |
| storage condition | avoid repeated freeze/thaw cycles |
| concentration | 400 μg/mL |
| color | clear colorless |
| NCBI accession no. | NM_003743 |
| UniProt accession no. | Q15788 |
| shipped in | dry ice |
| storage temp. | −70°C |
| Gene Information | human ... NCOA1(8648) |
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¥ 1573.49
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¥ 9207.92
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