Anti-PSMD4 antibody produced in rabbit,100UL,SAB5701473-100UL,Sigma

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订货号 0BT3645
品牌型号 Sigma SAB5701473-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. Pseudogenes have been identified on chromosomes 10 and 21. [provided by RefSeq, Jul 2008]


Immunogen

A synthesized peptide derived from human PSMD4


Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
antibody product typeprimary antibodies
clonemonoclonal
formliquid
species reactivitymouse, rat, human
concentration0.63 mg/mL
technique(s)immunohistochemistry: 1:50-1:200,western blot: 1:500-1:2000
UniProt accession no.P55036
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... PSMD4(5710)
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高度(mm)
重量(kg)
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