Anti-ACC1 antibody produced in rabbit,100UL,SAB5701307-100UL,Sigma

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订货号 0BT5941
品牌型号 Sigma SAB5701307-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5′ sequence and encoding distinct isoforms have been found for this gene.


Immunogen

A synthesized peptide derived from human ACC1


Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
antibody product typeprimary antibodies
clonemonoclonal
formliquid
species reactivityhuman, rat
concentration1.14 mg/mL
technique(s)immunohistochemistry: 1:50-1:200,western blot: 1:500-1:2000
UniProt accession no.Q13085
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... ACC1(31)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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