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General description
Interleukin-21 (IL-21) is a pleiotropic cytokine. It belongs to the common γ-chain cytokines with broad pleiotropic actions. This gene is located on human chromosome 4q27.
Application
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
Interleukin-21 (IL-21) regulates chronic viral infection, thereby plays a major role for immune responses in a mouse model of HBV (hepatitis B virus) infection. This gene is linked to celiac disease, rheumatoid arthritis (RA), type 1 diabetes mellitus (type 1 DM) and psoriatic arthritis. IL-21 has the ability to promote maturation and increase the cytotoxicity of CD8+ T cells and natural killer (NK) cells.
The antibody pair provided in this kit recognizes Human Interleukin-21.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
| species reactivity | human |
| packaging | kit of 96 wells (12 strips x 8 wells) |
| technique(s) | ELISA: suitable |
| input | sample type serum sample type plasma sample type cell culture supernatant(s) |
| assay range | inter-assay cv: <12% intra-assay cv: <10% sensitivity: 110 pg/mL standard curve range: 125-8000 pg/mL |
| detection method | colorimetric |
| shipped in | wet ice |
| storage temp. | −20°C |
| Gene Information | human ... IL21(59067) |
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