Anti-XRCC1 Antibody, clone 2X1U4, Rabbit Monoclonal,100UL,SAB5702395-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BT7713
品牌型号 Sigma SAB5702395-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human XRCC1 (P18887).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


Application

WB


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
materialcolorless
clone2X1U4, monoclonal
formliquid
mol wt 82 kDa
species reactivityrat, human
concentration0.93mg/mL
technique(s)western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceMPEIRLRHVVSCSSQDSTHCAENLLKADTYRKWRAAKAGEKTISVVLQLEKEEQIHSVDIGNDGSAFVEVLVGSSAGGAGEQDYEVLLVTSSFMSPSESR
UniProt accession no.P18887
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... XRCC1(7515)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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